GO:0004108 'citrate (Si)-synthase activity'
| Cvterm details |
| Term id | GO:0004108 |
| Term name | citrate (Si)-synthase activity |
| Term definition | Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group. |
| Comment |
Synonyms
(R)-citric synthase activity EXACT EC:2.3.3.1
acetyl-CoA:oxaloacetate C-acetyltransferase thioester-hydrolysing, (pro-S)-carboxymethyl forming RELATED EC:2.3.3.1
citrate condensing enzyme activity EXACT EC:2.3.3.1
citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)->acetyl-CoA) activity EXACT EC:2.3.3.1
citrate oxaloacetate-lyase ((pro-3S)-CH2COO-rightacetyl-CoA) EXACT EC:2.3.3.1
citrate oxaloacetate-lyase (pro-3S)-CH2COOrightacetyl-CoA RELATED EC:2.3.3.1
citrate oxaloacetate-lyase, CoA-acetylating activity EXACT EC:2.3.3.1
citrate synthase activity BROAD EC:2.3.3.1
citrate synthetase activity EXACT EC:2.3.3.1
citric synthase activity EXACT EC:2.3.3.1
citric-condensing enzyme activity EXACT EC:2.3.3.1
citrogenase activity EXACT EC:2.3.3.1
condensing enzyme activity BROAD EC:2.3.3.1
oxalacetic transacetase activity EXACT EC:2.3.3.1
oxaloacetate transacetase activity EXACT EC:2.3.3.1
"(R)-citric synthase activity" EXACT [EC:2.3.3.1]
"acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming]" RELATED [EC:2.3.3.1]
"citrate condensing enzyme activity" EXACT [EC:2.3.3.1]
"citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)->acetyl-CoA) activity" EXACT [EC:2.3.3.1]
"citrate oxaloacetate-lyase ((pro-3S)-CH2COO-rightacetyl-CoA)" EXACT [EC:2.3.3.1]
"citrate oxaloacetate-lyase [(pro-3S)-CH2COOrightacetyl-CoA]" RELATED [EC:2.3.3.1]
"citrate oxaloacetate-lyase, CoA-acetylating activity" EXACT [EC:2.3.3.1]
"citrate synthase activity" BROAD [EC:2.3.3.1]
"citrate synthetase activity" EXACT [EC:2.3.3.1]
"citric synthase activity" EXACT [EC:2.3.3.1]
"citric-condensing enzyme activity" EXACT [EC:2.3.3.1]
"citrogenase activity" EXACT [EC:2.3.3.1]
"condensing enzyme activity" BROAD [EC:2.3.3.1]
"oxalacetic transacetase activity" EXACT [EC:2.3.3.1]
"oxaloacetate transacetase activity" EXACT [EC:2.3.3.1]
Definition dbxrefs
Related dbxrefs
MetaCyc:CITSYN-RXN
Reactome:REACT_100557 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Mus musculus"
Reactome:REACT_100736 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Staphylococcus aureus N315"
Reactome:REACT_103631 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Xenopus tropicalis"
Reactome:REACT_107569 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Rattus norvegicus"
Reactome:REACT_108814 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Bos taurus"
Reactome:REACT_115605 "acetyl-CoA + H2O + oxaloacetate => citrate + CoA, Gallus gallus"
Reactome:REACT_1282 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Homo sapiens"
Reactome:REACT_32191 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Drosophila melanogaster"
Reactome:REACT_33399 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Danio rerio"
Reactome:REACT_81174 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Dictyostelium discoideum"
Reactome:REACT_81802 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Plasmodium falciparum"
Reactome:REACT_83386 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Oryza sativa"
Reactome:REACT_87177 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Arabidopsis thaliana"
Reactome:REACT_88391 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Caenorhabditis elegans"
Reactome:REACT_91540 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Canis familiaris"
Reactome:REACT_94285 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Schizosaccharomyces pombe"
Reactome:REACT_96879 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Sus scrofa"
RHEA:16848
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GO:0003674 molecular_function 
is_a GO:0003824 catalytic activity is_a GO:0016740 transferase activity is_a GO:0016746 transferase activity, transferring acyl groups is_a GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer 
is_a GO:0004108 citrate (Si)-synthase activity |
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