Term id	GO:0004842
Term name	ubiquitin-protein ligase activity
Term definition	Catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
Comment

Synonyms
anaphase-promoting complex activity NARROW GOC:dph, GOC:tairtb
E2 NARROW
E3 NARROW
ubiquitin activity RELATED EC:6.3.2.19
ubiquitin conjugating enzyme activity EXACT
ubiquitin ligase activity EXACT
ubiquitin protein ligase activity EXACT
ubiquitin protein-ligase activity EXACT
ubiquitin-conjugating enzyme activity EXACT
ubiquitin-ligase activity EXACT
ubiquitin:protein-lysine N-ligase (AMP-forming) activity EXACT EC:6.3.2.19
"anaphase-promoting complex activity" NARROW [GOC:dph, GOC:tairtb]
"E2" NARROW []
"E3" NARROW []
"ubiquitin activity" RELATED [EC:6.3.2.19]
"ubiquitin conjugating enzyme activity" EXACT []
"ubiquitin ligase activity" EXACT []
"ubiquitin protein ligase activity" EXACT []
"ubiquitin protein-ligase activity" EXACT []
"ubiquitin-conjugating enzyme activity" EXACT []
"ubiquitin-ligase activity" EXACT []
"ubiquitin:protein-lysine N-ligase (AMP-forming) activity" EXACT [EC:6.3.2.19]

Definition dbxrefs

Related dbxrefs
GO:0004840
GO:0004841
KEGG:R03876
MetaCyc:UBIQUITIN--PROTEIN-LIGASE-RXN
Reactome:REACT_100004 "Ubiquitination of Cyclin B by phospho-APC/C
Reactome:REACT_100102 "Ubiquitination of stimulated EGFR (CBL
Reactome:REACT_100126 "Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8, Taeniopygia guttata"
Reactome:REACT_100359 "Monoubiquitination of FANCI by the FA ubiquitin ligase complex, Mus musculus"
Reactome:REACT_100699 "Activated TRAF6 recruits TAK1complex by binding to ubiquitin receptors of TAB2/TAB3, Sus scrofa"
Reactome:REACT_100823 "Ubiquitination of Cyclin A by APC/C
Reactome:REACT_100856 "CBL ubiquitinates Sprouty, Danio rerio"
Reactome:REACT_101110 "Ubiquitination of Cyclin B by phospho-APC/C
Reactome:REACT_101216 "CBL ubiquitinates Sprouty, Rattus norvegicus"
Reactome:REACT_101217 "CBL binds and ubiquitinates phosphorylated Sprouty, Rattus norvegicus"
Reactome:REACT_101822 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Mus musculus"
Reactome:REACT_101849 "Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8, Drosophila melanogaster"
Reactome:REACT_102186 "Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8, Xenopus tropicalis"
Reactome:REACT_102220 "Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling, Xenopus tropicalis"
Reactome:REACT_102841 "Ubiquitination of stimulated EGFR (CBL
Reactome:REACT_103261 "Autoubiquitination of phospho-COP1(Ser-387 ), Bos taurus"
Reactome:REACT_103376 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Taeniopygia guttata"
Reactome:REACT_103483 "Ubiquitination of PER Proteins, Gallus gallus"
Reactome:REACT_103721 "CBL-mediated ubiquitination of CIN85, Rattus norvegicus"
Reactome:REACT_103809 "Ubiquitination of cell cycle proteins targeted by the APC/C
Reactome:REACT_104185 "Monoubiquitination of FANCD2 by the FA ubiquitin ligase complex, Canis familiaris"
Reactome:REACT_104518 "Ubiquitination of Securin by phospho-APC/C
Reactome:REACT_104803 "CBL ubiquitinates Sprouty, Canis familiaris"
Reactome:REACT_104984 "Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8, Danio rerio"
Reactome:REACT_104994 "Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling, Mus musculus"
Reactome:REACT_105370 "Multiubiquitination of APC/C-associated Cdh1, Danio rerio"
Reactome:REACT_105620 "Multiubiquitination of APC/C-associated Cdh1, Taeniopygia guttata"
Reactome:REACT_106156 "Ubiquitination of cell cycle proteins targeted by the APC/C
Reactome:REACT_106407 "CBL binds and ubiquitinates phosphorylated Sprouty, Mus musculus"
Reactome:REACT_106416 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Sus scrofa"
Reactome:REACT_106527 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Gallus gallus"
Reactome:REACT_106906 "Ubiquitination of Cyclin B by phospho-APC/C
Reactome:REACT_107379 "Ubiquitination of Securin by phospho-APC/C
Reactome:REACT_107643 "Ubiquitination of phospho-p27/p21, Danio rerio"
Reactome:REACT_107829 "Multiubiquitination of APC/C-associated Cdh1, Rattus norvegicus"
Reactome:REACT_108396 "TRAF6 polyubiquitinates NRIF, Bos taurus"
Reactome:REACT_108446 "Ubiquitination of Cyclin A by APC/C
Reactome:REACT_108589 "Ubiquitination of cell cycle proteins targeted by the APC/C
Reactome:REACT_108657 "Activated TRAF6 recruits TAK1complex by binding to ubiquitin receptors of TAB2/TAB3, Danio rerio"
Reactome:REACT_109007 "Monoubiquitination of FANCD2 by the FA ubiquitin ligase complex, Gallus gallus"
Reactome:REACT_109071 "Ubiquitination of Securin by phospho-APC/C
Reactome:REACT_109354 "Ubiquitination of Emi1 by SCF-beta-TrCP, Rattus norvegicus"
Reactome:REACT_109539 "Ubiquitination of Emi1 by SCF-beta-TrCP, Canis familiaris"
Reactome:REACT_109637 "Autoubiquitination of phospho-COP1(Ser-387 ), Oryza sativa"
Reactome:REACT_109798 "CBL-mediated ubiquitination of CIN85, Mus musculus"
Reactome:REACT_110158 "Ubiquitination of Cyclin B by phospho-APC/C
Reactome:REACT_110535 "Autoubiquitination of phospho-COP1(Ser-387 ), Xenopus tropicalis"
Reactome:REACT_110749 "Activated TRAF6 recruits TAK1complex by binding to ubiquitin receptors of TAB2/TAB3, Rattus norvegicus"
Reactome:REACT_111089 "Ubiquitination of p130 (RBL2) by SCF (Skp2), Homo sapiens"
Reactome:REACT_111141 "Phosphorylated SPRY2 is ubiquitinated by CBL, Homo sapiens"
Reactome:REACT_111231 "CBL ubiquitinates FRS2 and FGFR, Homo sapiens"
Reactome:REACT_112355 "Auto-ubiquitination of TRAF6, Bos taurus"
Reactome:REACT_112414 "Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling, Danio rerio"
Reactome:REACT_112448 "Ubiquitination of NEMO by TRAF6, Xenopus tropicalis"
Reactome:REACT_112669 "CBL ubiquitinates Sprouty, Drosophila melanogaster"
Reactome:REACT_113192 "CBL ubiquitinates Sprouty, Bos taurus"
Reactome:REACT_113956 "Monoubiquitination of FANCI by the FA ubiquitin ligase complex, Xenopus tropicalis"
Reactome:REACT_114042 "Auto-ubiquitination of TRAF6, Gallus gallus"
Reactome:REACT_114074 "CBL ubiquitinates Sprouty, Gallus gallus"
Reactome:REACT_114376 "Ubiquitination of Cyclin A by APC/C
Reactome:REACT_114678 "Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling, Danio rerio"
Reactome:REACT_115172 "Multiubiquitination of Nek2A, Dictyostelium discoideum"
Reactome:REACT_115175 "Ubiquitination of NEMO by TRAF6, Bos taurus"
Reactome:REACT_115543 "ISGylation of E2 conjugating enzymes, Homo sapiens"
Reactome:REACT_115557 "CUL5 mediates ubiquitination of ERBB2, Homo sapiens"
Reactome:REACT_115599 "RNF41 ubiquitinates activated ERBB3, Homo sapiens"
Reactome:REACT_115658 "ISGylation of host protein filamin B, Homo sapiens"
Reactome:REACT_115732 "Inefficient ubiquitination of ligand-responsive EGFR mutants by phosphorylated CBL, Homo sapiens"
Reactome:REACT_115802 "Monoubiquitination of FancD2, Gallus gallus"
Reactome:REACT_115843 "ISGylation of protein phosphatase 1 beta (PP2CB), Homo sapiens"
Reactome:REACT_115889 "NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer, Homo sapiens"
Reactome:REACT_115890 "ISGylation of host proteins, Homo sapiens"
Reactome:REACT_115934 "ISGylation of IRF3, Homo sapiens"
Reactome:REACT_115952 "RNF41 ubiquitinates ERBB3, Homo sapiens"
Reactome:REACT_115963 "Self-ubiquitination of RNF41, Homo sapiens"
Reactome:REACT_115965 "ISGylation of viral protein NS1, Homo sapiens"
Reactome:REACT_116015 "CHIP (STUB1) mediates ubiquitination of ERBB2, Homo sapiens"
Reactome:REACT_116054 "ERBB4 ubiquitination by WWP1/ITCH, Homo sapiens"
Reactome:REACT_116086 "Monoubiquitination of PCNA, Gallus gallus"
Reactome:REACT_116132 "Activation of ISG15 by UBE1L E1 ligase, Homo sapiens"
Reactome:REACT_12038 "Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8, Homo sapiens"
Reactome:REACT_12048 "Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling, Homo sapiens"
Reactome:REACT_12381 "CBL ubiquitinates Sprouty, Homo sapiens"
Reactome:REACT_12432 "CBL binds and ubiquitinates phosphorylated Sprouty, Homo sapiens"
Reactome:REACT_12451 "CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix, Homo sapiens"
Reactome:REACT_12515 "Ubiquitination of stimulated EGFR (CBL), Homo sapiens"
Reactome:REACT_12520 "CBL-mediated ubiquitination of CIN85, Homo sapiens"
Reactome:REACT_12553 "Ubiquitination of NEMO by TRAF6, Homo sapiens"
Reactome:REACT_12562 "Ubiquitination of stimulated EGFR (CBL
Reactome:REACT_12595 "Auto-ubiquitination of TRAF6, Homo sapiens"
Reactome:REACT_13487 "Ubiquitination of PAK-2p34, Oryctolagus cuniculus"
Reactome:REACT_13488 "TRAF6 polyubiquitinates NRIF, Homo sapiens"
Reactome:REACT_13600 "Ubiquitination of PAK-2p34, Homo sapiens"
Reactome:REACT_18367 "Monoubiquitination of FANCI by the FA ubiquitin ligase complex, Homo sapiens"
Reactome:REACT_18429 "Monoubiquitination of FANCD2 by the FA ubiquitin ligase complex, Homo sapiens"
Reactome:REACT_20581 "Autoubiquitination of phospho-COP1(Ser-387 ), Homo sapiens"
Reactome:REACT_21364 "Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation, Homo sapiens"
Reactome:REACT_22381 "Pellino ubiquitinates IRAK1, Homo sapiens"
Reactome:REACT_22407 "Beta-TrCP ubiquitinates then dissociates from p-NFKB p105, Homo sapiens"
Reactome:REACT_22430 "TRAF6 auto-ubiquitinates with Lys63-linked polyubiquitin chains, Homo sapiens"
Reactome:REACT_24932 "PIN1 mediated IRF3 degradation, Homo sapiens"
Reactome:REACT_24996 "Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane, Homo sapiens"
Reactome:REACT_25022 "Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2, Homo sapiens"
Reactome:REACT_25090 "TRAF6 ubiquitinqtes IRF7 in a K63-dependent manner following TLR7/8 or 9 stimulation, Homo sapiens"
Reactome:REACT_25128 "Auto ubiquitination of oligo TRAF6 bound to p-IRAK2, Gallus gallus"
Reactome:REACT_25143 "Ubiquitination of PER Proteins, Homo sapiens"
Reactome:REACT_25177 "RNF125 mediated ubiquitination of RIG-I, MDA5 and IPS-1, Mus musculus"
Reactome:REACT_25220 "K-63-linked polyubiquitination of RIG-I, Homo sapiens"
Reactome:REACT_25252 "RNF125 mediated ubiquitination of RIG-I, MDA5 and IPS-1, Homo sapiens"
Reactome:REACT_25317 "Activated chicken TRAF6 synthesizes free K63bound poly_Ub chains within the complex dsRNA
Reactome:REACT_25362 "Activated TRAF6 synthesizes unanchored polyubiquitin chains, Homo sapiens"
Reactome:REACT_25377 "Auto ubiquitination of the TRAF6 within the complex viral dsRNA
Reactome:REACT_25386 "Activated chicken TRAF6 synthesizes free K63bound poly_Ub chains within the complex p-IRAK2
Reactome:REACT_25398 "Recruitment of AIP4 and K-48 ubiquitination of MAVS/IPS-1, Homo sapiens"
Reactome:REACT_27202 "Autoubiquitination of oligoTRAF6 bound to p-IRAK2, Gallus gallus"
Reactome:REACT_28038 "Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8, Mus musculus"
Reactome:REACT_28057 "Ubiquitination of NEMO by TRAF6, Danio rerio"
Reactome:REACT_28632 "Monoubiquitination of FANCI by the FA ubiquitin ligase complex, Gallus gallus"
Reactome:REACT_28669 "Ubiquitination of cell cycle proteins targeted by the APC/C
Reactome:REACT_28992 "Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling, Bos taurus"
Reactome:REACT_29045 "CBL ubiquitinates Sprouty, Xenopus tropicalis"
Reactome:REACT_30173 "Monoubiquitination of FANCI by the FA ubiquitin ligase complex, Danio rerio"
Reactome:REACT_30590 "Ubiquitination of PER Proteins, Rattus norvegicus"
Reactome:REACT_30651 "Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8, Canis familiaris"
Reactome:REACT_30747 "Ubiquitination of Securin by phospho-APC/C
Reactome:REACT_31133 "Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling, Bos taurus"
Reactome:REACT_31520 "TRAF6 polyubiquitinates NRIF, Gallus gallus"
Reactome:REACT_31622 "Monoubiquitination of FANCD2 by the FA ubiquitin ligase complex, Mus musculus"
Reactome:REACT_31985 "Ubiquitination of cell cycle proteins targeted by the APC/C
Reactome:REACT_32642 "CBL ubiquitinates Sprouty, Taeniopygia guttata"
Reactome:REACT_32728 "Ubiquitination of cell cycle proteins targeted by the APC/C
Reactome:REACT_32748 "Multiubiquitination of APC/C-associated Cdh1, Mus musculus"
Reactome:REACT_33018 "Auto-ubiquitination of TRAF6, Xenopus tropicalis"
Reactome:REACT_33373 "Monoubiquitination of FANCI by the FA ubiquitin ligase complex, Taeniopygia guttata"
Reactome:REACT_33406 "Ubiquitination of NEMO by TRAF6, Mus musculus"
Reactome:REACT_33468 "Multiubiquitination of APC/C-associated Cdh1, Bos taurus"
Reactome:REACT_33488 "CBL binds and ubiquitinates phosphorylated Sprouty, Danio rerio"
Reactome:REACT_34498 "Multiubiquitination of Nek2A, Taeniopygia guttata"
Reactome:REACT_62571 "Ubiquitination of stimulated EGFR (CBL
Reactome:REACT_6723 "Ubiquitination of Securin by phospho-APC/C
Reactome:REACT_6735 "Ubiquitination of Cyclin B by phospho-APC/C
Reactome:REACT_6786 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Homo sapiens"
Reactome:REACT_6791 "Multiubiquitination of APC/C-associated Cdh1, Homo sapiens"
Reactome:REACT_6824 "Ubiquitination of Cyclin A by APC/C
Reactome:REACT_6827 "Ubiquitination of Emi1 by SCF-beta-TrCP, Homo sapiens"
Reactome:REACT_6857 "Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling, Homo sapiens"
Reactome:REACT_6914 "Ubiquitination of cell cycle proteins targeted by the APC/C
Reactome:REACT_6921 "Activated TRAF6 recruits TAK1complex by binding to ubiquitin receptors of TAB2/TAB3, Homo sapiens"
Reactome:REACT_715 "Ubiquitination of Cyclin D1, Homo sapiens"
Reactome:REACT_75782 "E1 mediated ubiquitin activation, Homo sapiens"
Reactome:REACT_75847 "Polyubiquitination of substrate, Homo sapiens"
Reactome:REACT_75901 "Transfer of Ub from E2 to substrate and release of E2, Homo sapiens"
Reactome:REACT_75924 "RIP2 induces K63-linked ubiquitination of NEMO, Homo sapiens"
Reactome:REACT_76990 "Autoubiquitination of phospho-COP1(Ser-387 ), Gallus gallus"
Reactome:REACT_77058 "Ubiquitination of cell cycle proteins targeted by the APC/C
Reactome:REACT_78171 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Canis familiaris"
Reactome:REACT_78216 "Ubiquitination of Securin by phospho-APC/C
Reactome:REACT_78347 "Ubiquitination of PER Proteins, Canis familiaris"
Reactome:REACT_78373 "Ubiquitination of stimulated EGFR (CBL), Xenopus tropicalis"
Reactome:REACT_78391 "TRAF6 polyubiquitinates NRIF, Mus musculus"
Reactome:REACT_78475 "Ubiquitination of cell cycle proteins targeted by the APC/C
Reactome:REACT_79393 "Multiubiquitination of APC/C-associated Cdh1, Drosophila melanogaster"
Reactome:REACT_79631 "Autoubiquitination of phospho-COP1(Ser-387 ), Danio rerio"
Reactome:REACT_79673 "Ubiquitination of phospho-p27/p21, Rattus norvegicus"
Reactome:REACT_79773 "Ubiquitination of Cyclin A by APC/C
Reactome:REACT_79781 "Multiubiquitination of APC/C-associated Cdh1, Oryza sativa"
Reactome:REACT_7995 "Multiubiquitination of Nek2A, Homo sapiens"
Reactome:REACT_80157 "Multiubiquitination of APC/C-associated Cdh1, Xenopus tropicalis"
Reactome:REACT_80228 "Monoubiquitination of FANCI by the FA ubiquitin ligase complex, Rattus norvegicus"
Reactome:REACT_80230 "Auto-ubiquitination of TRAF6, Mus musculus"
Reactome:REACT_80243 "Ubiquitination of Cyclin A by APC/C
Reactome:REACT_80572 "CBL-mediated ubiquitination of CIN85, Taeniopygia guttata"
Reactome:REACT_80798 "Autoubiquitination of phospho-COP1(Ser-387 ), Canis familiaris"
Reactome:REACT_80813 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Rattus norvegicus"
Reactome:REACT_81041 "CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix, Mus musculus"
Reactome:REACT_81332 "Ubiquitination of phospho-p27/p21, Mus musculus"
Reactome:REACT_81489 "Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8, Bos taurus"
Reactome:REACT_81526 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Bos taurus"
Reactome:REACT_81796 "Ubiquitination of Securin by phospho-APC/C
Reactome:REACT_81809 "Ubiquitination of Securin by phospho-APC/C
Reactome:REACT_82103 "Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling, Sus scrofa"
Reactome:REACT_82502 "Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling, Xenopus tropicalis"
Reactome:REACT_82956 "CBL-mediated ubiquitination of CIN85, Bos taurus"
Reactome:REACT_83121 "Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling, Drosophila melanogaster"
Reactome:REACT_83886 "Ubiquitination of Emi1 by SCF-beta-TrCP, Mus musculus"
Reactome:REACT_83914 "Ubiquitination of phospho-p27/p21, Bos taurus"
Reactome:REACT_84110 "Multiubiquitination of Nek2A, Drosophila melanogaster"
Reactome:REACT_84282 "Ubiquitination of stimulated EGFR (CBL), Danio rerio"
Reactome:REACT_84479 "Multiubiquitination of Nek2A, Rattus norvegicus"
Reactome:REACT_84482 "Multiubiquitination of Nek2A, Xenopus tropicalis"
Reactome:REACT_84826 "Ubiquitination of stimulated EGFR (CBL), Mus musculus"
Reactome:REACT_85057 "Autoubiquitination of phospho-COP1(Ser-387 ), Taeniopygia guttata"
Reactome:REACT_85163 "Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling, Rattus norvegicus"
Reactome:REACT_85194 "Ubiquitination of Cyclin A by APC/C
Reactome:REACT_85337 "CBL binds and ubiquitinates phosphorylated Sprouty, Canis familiaris"
Reactome:REACT_85348 "CBL-mediated ubiquitination of CIN85, Gallus gallus"
Reactome:REACT_85498 "Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8, Rattus norvegicus"
Reactome:REACT_86043 "Ubiquitination of Securin by phospho-APC/C
Reactome:REACT_86192 "Ubiquitination of phospho-p27/p21, Canis familiaris"
Reactome:REACT_86281 "Ubiquitination of Emi1 by SCF-beta-TrCP, Bos taurus"
Reactome:REACT_86879 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Danio rerio"
Reactome:REACT_87217 "Ubiquitination of Cyclin A by APC/C
Reactome:REACT_87236 "Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling, Mus musculus"
Reactome:REACT_87349 "Ubiquitination of Cyclin B by phospho-APC/C
Reactome:REACT_87486 "Monoubiquitination of FANCI by the FA ubiquitin ligase complex, Bos taurus"
Reactome:REACT_87663 "Multiubiquitination of Nek2A, Gallus gallus"
Reactome:REACT_87845 "Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling, Rattus norvegicus"
Reactome:REACT_88589 "Autoubiquitination of phospho-COP1(Ser-387 ), Rattus norvegicus"
Reactome:REACT_88911 "CBL ubiquitinates Sprouty, Mus musculus"
Reactome:REACT_88971 "Monoubiquitination of FANCD2 by the FA ubiquitin ligase complex, Rattus norvegicus"
Reactome:REACT_89066 "Ubiquitination of Securin by phospho-APC/C
Reactome:REACT_89086 "Ubiquitination of stimulated EGFR (CBL), Canis familiaris"
Reactome:REACT_89128 "TRAF6 polyubiquitinates NRIF, Rattus norvegicus"
Reactome:REACT_89304 "Ubiquitination of Emi1 by SCF-beta-TrCP, Drosophila melanogaster"
Reactome:REACT_89324 "CBL-mediated ubiquitination of CIN85, Danio rerio"
Reactome:REACT_89540 "Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling, Drosophila melanogaster"
Reactome:REACT_9026 "Ubiquitination of phospho-p27/p21, Homo sapiens"
Reactome:REACT_90441 "CBL-mediated ubiquitination of CIN85, Canis familiaris"
Reactome:REACT_90505 "Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8, Gallus gallus"
Reactome:REACT_9063 "Ubiquitination of CD4 by Vpu
Reactome:REACT_90742 "Ubiquitination of PER Proteins, Drosophila melanogaster"
Reactome:REACT_90880 "Monoubiquitination of FANCD2 by the FA ubiquitin ligase complex, Danio rerio"
Reactome:REACT_91216 "Ubiquitination of cell cycle proteins targeted by the APC/C
Reactome:REACT_91336 "Multiubiquitination of APC/C-associated Cdh1, Gallus gallus"
Reactome:REACT_91446 "Ubiquitination of stimulated EGFR (CBL
Reactome:REACT_91686 "Ubiquitination of Cyclin B by phospho-APC/C
Reactome:REACT_91754 "Multiubiquitination of Nek2A, Danio rerio"
Reactome:REACT_91854 "Activated TRAF6 recruits TAK1complex by binding to ubiquitin receptors of TAB2/TAB3, Bos taurus"
Reactome:REACT_91885 "Ubiquitination of Cyclin A by APC/C
Reactome:REACT_92022 "Multiubiquitination of Nek2A, Bos taurus"
Reactome:REACT_92097 "Activated TRAF6 recruits TAK1complex by binding to ubiquitin receptors of TAB2/TAB3, Gallus gallus"
Reactome:REACT_92278 "CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix, Rattus norvegicus"
Reactome:REACT_92341 "Ubiquitination of cell cycle proteins targeted by the APC/C
Reactome:REACT_92445 "CBL binds and ubiquitinates phosphorylated Sprouty, Xenopus tropicalis"
Reactome:REACT_92638 "Autoubiquitination of phospho-COP1(Ser-387 ), Sus scrofa"
Reactome:REACT_92641 "Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling, Sus scrofa"
Reactome:REACT_92734 "Autoubiquitination of phospho-COP1(Ser-387 ), Dictyostelium discoideum"
Reactome:REACT_92878 "Multiubiquitination of APC/C-associated Cdh1, Canis familiaris"
Reactome:REACT_93 "Ubiquitination of phosphorylated Cdc25A, Homo sapiens"
Reactome:REACT_93088 "Autoubiquitination of phospho-COP1(Ser-387 ), Mus musculus"
Reactome:REACT_93091 "Monoubiquitination of FANCI by the FA ubiquitin ligase complex, Canis familiaris"
Reactome:REACT_93808 "Ubiquitination of stimulated EGFR (CBL
Reactome:REACT_93823 "Ubiquitination of PER Proteins, Xenopus tropicalis"
Reactome:REACT_93940 "CBL-mediated ubiquitination of CIN85, Drosophila melanogaster"
Reactome:REACT_93965 "Monoubiquitination of FANCD2 by the FA ubiquitin ligase complex, Bos taurus"
Reactome:REACT_94143 "TRAF6 polyubiquitinates NRIF, Taeniopygia guttata"
Reactome:REACT_94165 "CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix, Danio rerio"
Reactome:REACT_94183 "Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8, Sus scrofa"
Reactome:REACT_94202 "Multiubiquitination of Nek2A, Canis familiaris"
Reactome:REACT_94479 "Ubiquitination of PER Proteins, Bos taurus"
Reactome:REACT_94486 "Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling, Canis familiaris"
Reactome:REACT_94525 "CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix, Xenopus tropicalis"
Reactome:REACT_94687 "Ubiquitination of Cyclin A by APC/C
Reactome:REACT_9471 "Multi-ubiquitination of APOBEC3G, Homo sapiens"
Reactome:REACT_94788 "Monoubiquitination of FANCD2 by the FA ubiquitin ligase complex, Taeniopygia guttata"
Reactome:REACT_94789 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Drosophila melanogaster"
Reactome:REACT_94816 "Activated TRAF6 recruits TAK1complex by binding to ubiquitin receptors of TAB2/TAB3, Taeniopygia guttata"
Reactome:REACT_94864 "Ubiquitination of cell cycle proteins targeted by the APC/C
Reactome:REACT_95005 "Ubiquitination of phospho-p27/p21, Sus scrofa"
Reactome:REACT_95022 "Multiubiquitination of Nek2A, Mus musculus"
Reactome:REACT_95267 "Ubiquitination of phospho-p27/p21, Xenopus tropicalis"
Reactome:REACT_95302 "Ubiquitination of Emi1 by SCF-beta-TrCP, Taeniopygia guttata"
Reactome:REACT_95501 "Ubiquitination of Cyclin A by APC/C
Reactome:REACT_95529 "Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling, Canis familiaris"
Reactome:REACT_95866 "Ubiquitination of stimulated EGFR (CBL
Reactome:REACT_96059 "Ubiquitination of stimulated EGFR (CBL
Reactome:REACT_96134 "Activated TRAF6 recruits TAK1complex by binding to ubiquitin receptors of TAB2/TAB3, Xenopus tropicalis"
Reactome:REACT_96591 "CBL-mediated ubiquitination of CIN85, Xenopus tropicalis"
Reactome:REACT_96771 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Xenopus tropicalis"
Reactome:REACT_97330 "Ubiquitination of Emi1 by SCF-beta-TrCP, Xenopus tropicalis"
Reactome:REACT_97494 "Ubiquitination of stimulated EGFR (CBL
Reactome:REACT_97971 "Ubiquitination of Cyclin B by phospho-APC/C
Reactome:REACT_98364 "Auto-ubiquitination of TRAF6, Danio rerio"
Reactome:REACT_98491 "Activated TRAF6 recruits TAK1complex by binding to ubiquitin receptors of TAB2/TAB3, Mus musculus"
Reactome:REACT_98502 "Activated TRAF6 recruits TAK1complex by binding to ubiquitin receptors of TAB2/TAB3, Canis familiaris"
Reactome:REACT_98894 "Ubiquitination of Cyclin B by phospho-APC/C
Reactome:REACT_98993 "Ubiquitination of PER Proteins, Taeniopygia guttata"
Reactome:REACT_99285 "Ubiquitination of stimulated EGFR (CBL), Rattus norvegicus"
Reactome:REACT_99567 "Ubiquitination of Emi1 by SCF-beta-TrCP, Gallus gallus"
Reactome:REACT_99825 "Ubiquitination of Cyclin B by phospho-APC/C

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