GO:0031047 'RNA-mediated gene silencing'

Cvterm details 
Term idGO:0031047
Term nameRNA-mediated gene silencing
Term definitionA process in which an RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation.
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Synonyms
RNA-mediated gene silencing EXACT GOC:dph, GOC:tb
"RNA-mediated gene silencing" EXACT [GOC:dph, GOC:tb]
gene silencing by RNA
RNA-dependent gene silencing

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GO:0008150 biological_process
is_a GO:0008152 metabolic process
NEGATIVELY_REGULATES GO:0009892 negative regulation of metabolic process
is_a GO:0010605 negative regulation of macromolecule metabolic process
is_a GO:0010629 negative regulation of gene expression
is_a GO:0031047 RNA-mediated gene silencing
is_a GO:0071704 organic substance metabolic process
is_a GO:0043170 macromolecule metabolic process
NEGATIVELY_REGULATES GO:0010605 negative regulation of macromolecule metabolic process
is_a GO:0010629 negative regulation of gene expression
is_a GO:0031047 RNA-mediated gene silencing
REGULATES GO:0060255 regulation of macromolecule metabolic process
is_a GO:0010468 regulation of gene expression
is_a GO:0010629 negative regulation of gene expression
is_a GO:0031047 RNA-mediated gene silencing
is_a GO:0010605 negative regulation of macromolecule metabolic process
is_a GO:0010629 negative regulation of gene expression
is_a GO:0031047 RNA-mediated gene silencing
is_a GO:0010467 gene expression
REGULATES GO:0010468 regulation of gene expression
is_a GO:0010629 negative regulation of gene expression
is_a GO:0031047 RNA-mediated gene silencing
NEGATIVELY_REGULATES GO:0010629 negative regulation of gene expression
is_a GO:0031047 RNA-mediated gene silencing
REGULATES GO:0019222 regulation of metabolic process
is_a GO:0009892 negative regulation of metabolic process
is_a GO:0010605 negative regulation of macromolecule metabolic process
is_a GO:0010629 negative regulation of gene expression
is_a GO:0031047 RNA-mediated gene silencing
is_a GO:0060255 regulation of macromolecule metabolic process
is_a GO:0010468 regulation of gene expression
is_a GO:0010629 negative regulation of gene expression
is_a GO:0031047 RNA-mediated gene silencing
is_a GO:0010605 negative regulation of macromolecule metabolic process
is_a GO:0010629 negative regulation of gene expression
is_a GO:0031047 RNA-mediated gene silencing
is_a GO:0065007 biological regulation
is_a GO:0050789 regulation of biological process
is_a GO:0048519 negative regulation of biological process
is_a GO:0009892 negative regulation of metabolic process
is_a GO:0010605 negative regulation of macromolecule metabolic process
is_a GO:0010629 negative regulation of gene expression
is_a GO:0031047 RNA-mediated gene silencing
is_a GO:0019222 regulation of metabolic process
is_a GO:0009892 negative regulation of metabolic process
is_a GO:0010605 negative regulation of macromolecule metabolic process
is_a GO:0010629 negative regulation of gene expression
is_a GO:0031047 RNA-mediated gene silencing
is_a GO:0060255 regulation of macromolecule metabolic process
is_a GO:0010468 regulation of gene expression
is_a GO:0010629 negative regulation of gene expression
is_a GO:0031047 RNA-mediated gene silencing
is_a GO:0010605 negative regulation of macromolecule metabolic process
is_a GO:0010629 negative regulation of gene expression
is_a GO:0031047 RNA-mediated gene silencing
NEGATIVELY_REGULATES GO:0048519 negative regulation of biological process
is_a GO:0009892 negative regulation of metabolic process
is_a GO:0010605 negative regulation of macromolecule metabolic process
is_a GO:0010629 negative regulation of gene expression
is_a GO:0031047 RNA-mediated gene silencing
REGULATES GO:0050789 regulation of biological process
is_a GO:0048519 negative regulation of biological process
is_a GO:0009892 negative regulation of metabolic process
is_a GO:0010605 negative regulation of macromolecule metabolic process
is_a GO:0010629 negative regulation of gene expression
is_a GO:0031047 RNA-mediated gene silencing
is_a GO:0019222 regulation of metabolic process
is_a GO:0009892 negative regulation of metabolic process
is_a GO:0010605 negative regulation of macromolecule metabolic process
is_a GO:0010629 negative regulation of gene expression
is_a GO:0031047 RNA-mediated gene silencing
is_a GO:0060255 regulation of macromolecule metabolic process
is_a GO:0010468 regulation of gene expression
is_a GO:0010629 negative regulation of gene expression
is_a GO:0031047 RNA-mediated gene silencing
is_a GO:0010605 negative regulation of macromolecule metabolic process
is_a GO:0010629 negative regulation of gene expression
is_a GO:0031047 RNA-mediated gene silencing
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